Research

Prediction Models


Clinical trials


Biomarkers


EHR tool evaluation


Database studies


Microbiome


Health disparities


Access


References

Afshar, M., Baker, K., Corral, J., Ross, E., Lowery, E., Gonzalez, R., Burnham, E. L., Callcut, R. A., Kornblith, L. Z., Hendrickson, C., Kovacs, E. J., and Joyce, C. (2022a), “Internal and External Validation of an Alcohol Biomarker for Screening in Trauma.” Annals of surgery, 276, e961–e968. https://doi.org/10.1097/SLA.0000000000004770.
Afshar, M., Burnham, E. L., Joyce, C., Clark, B. J., Yong, M., Gaydos, J., Cooper, R. S., Smith, G. S., Kovacs, E. J., and Lowery, E. M. (2017), “Cut-Point Levels of Phosphatidylethanol to Identify Alcohol Misuse in a Mixed Cohort Including Critically Ill Patients.” Alcoholism, clinical and experimental research, 41, 1745–1753. https://doi.org/10.1111/acer.13471.
Afshar, M., Burnham, E. L., Joyce, C., Gagnon, R., Dunn, R., Albright, J. M., Ramirez, L., Repine, J. E., Netzer, G., and Kovacs, E. J. (2019a), “Injury Characteristics and von Willebrand Factor for the Prediction of Acute Respiratory Distress Syndrome in Patients With Burn Injury: Development and Internal Validation.” Annals of surgery, 270, 1186–1193. https://doi.org/10.1097/SLA.0000000000002795.
Afshar, M., Joyce, C., Oakey, A., Formanek, P., Yang, P., Churpek, M. M., Cooper, R. S., Zelisko, S., Price, R., and Dligach, D. (2018), A Computable Phenotype for Acute Respiratory Distress Syndrome Using Natural Language Processing and Machine Learning. AMIA ... Annual Symposium proceedings. AMIA Symposium, 2018, 157–165.
Afshar, M., Phillips, A., Karnik, N., Mueller, J., To, D., Gonzalez, R., Price, R., Cooper, R., Joyce, C., and Dligach, D. (2019b), “Natural language processing and machine learning to identify alcohol misuse from the electronic health record in trauma patients: Development and internal validation.” Journal of the American Medical Informatics Association : JAMIA, 26, 254–261. https://doi.org/10.1093/jamia/ocy166.
Afshar, M., Sharma, B., Dligach, D., Oguss, M., Brown, R., Chhabra, N., Thompson, H. M., Markossian, T., Joyce, C., Churpek, M. M., and Karnik, N. S. (2022b), “Development and multimodal validation of a substance misuse algorithm for referral to treatment using artificial intelligence (SMART-AI): A retrospective deep learning study.” The Lancet. Digital health, 4, e426–e435. https://doi.org/10.1016/S2589-7500(22)00041-3.
Bajic, P., Van Kuiken, M. E., Burge, B. K., Kirshenbaum, E. J., Joyce, C. J., Wolfe, A. J., Branch, J. D., Bresler, L., and Farooq, A. V. (2020), “Male Bladder Microbiome Relates to Lower Urinary Tract Symptoms.” European urology focus, 6, 376–382. https://doi.org/10.1016/j.euf.2018.08.001.
Barnes, H. C., Wolff, B., Abdul-Rahim, O., Harrington, A., Hilt, E. E., Price, T. K., Halverson, T., Hochstedler, B. R., Pham, T., Acevedo-Alvarez, M., Joyce, C., Fitzgerald, C. M., Schreckenberger, P. C., Brubaker, L., Wolfe, A. J., and Mueller, E. R. (2021), “A Randomized Clinical Trial of Standard versus Expanded Cultures to Diagnose Urinary Tract Infections in Women.” The Journal of urology, 206, 1212–1221. https://doi.org/10.1097/JU.0000000000001949.
Borgese, M., Joyce, C., Anderson, E. E., Churpek, M. M., and Afshar, M. (2021), Bias Assessment and Correction in Machine Learning Algorithms: A Use-Case in a Natural Language Processing Algorithm to Identify Hospitalized Patients with Unhealthy Alcohol Use. AMIA ... Annual Symposium proceedings. AMIA Symposium, 2021, 247–254.
Bresler, L., Price, T. K., Hilt, E. E., Joyce, C., Fitzgerald, C. M., and Wolfe, A. J. (2019), “Female lower urinary tract microbiota do not associate with IC/PBS symptoms: A case-controlled study.” International urogynecology journal, 30, 1835–1842. https://doi.org/10.1007/s00192-019-03942-9.
Bresler, L., Westbay, L. C., Hekman, L., Joyce, C., and Fitzgerald, C. M. (2022), Acupuncture for female bladder pain syndrome: A randomized controlled trial. The Canadian journal of urology, 29, 11154–11161.
Bruce, W. J., Chang, V., Joyce, C. J., Cobb, A. N., Maduekwe, U. I., and Patel, P. A. (2018), “Age at Time of Craniosynostosis Repair Predicts Increased Complication Rate.” The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 55, 649–654. https://doi.org/10.1177/1055665617725215.
Burkhart, L., Coglianese, M., Kaelin, J., Moorhead, S., and Joyce, C. (2021), “Communicating Spiritual Care in the Electronic Health Record.” Computers, informatics, nursing : CIN, 39, 538–546. https://doi.org/10.1097/CIN.0000000000000707.
Charrow, A., Xia, F. D., Joyce, C., and Mostaghimi, A. (2017), “Diversity in Dermatology Clinical Trials: A Systematic Review.” JAMA dermatology, 153, 193–198. https://doi.org/10.1001/jamadermatol.2016.4129.
Charrow, A., Xia, F. D., Lu, J., Waul, M., Joyce, C., and Mostaghimi, A. (2019), “Differences in isotretinoin start, interruption, and early termination across race and sex in the iPLEDGE era.” PloS one, 14, e0210445. https://doi.org/10.1371/journal.pone.0210445.
Cocohoba, J., Pohlman, B., Tran, J. S., Kirkham, H., Joyce, C., Clark, K., and Stebbins, M. (2019), “Modeling specialty medicine access: Understanding key health system processes and players.” Journal of the American Pharmacists Association : JAPhA, 59, 43–50.e3. https://doi.org/10.1016/j.japh.2018.09.004.
Creadore, A., Desai, S., Li, S. J., Lee, K. J., Bui, A.-T. N., Villa-Ruiz, C., Lo, K., Zhou, G., Joyce, C., Resneck, J. S. J., Seiger, K., and Mostaghimi, A. (2021), “Insurance Acceptance, Appointment Wait Time, and Dermatologist Access Across Practice Types in the US.” JAMA dermatology, 157, 181–188. https://doi.org/10.1001/jamadermatol.2020.5173.
Creadore, A., Manjaly, P., Tkachenko, E., Li, D. G., Kaffenberger, B., Shinkai, K., Rosenbach, M., Joyce, C., and Mostaghimi, A. (2022), “The utility of augmented teledermatology to improve dermatologist diagnosis of cellulitis: A cross-sectional study.” Archives of dermatological research. https://doi.org/10.1007/s00403-022-02517-x.
Di Xia, F., Fuhlbrigge, M., Dommasch, E., Joyce, C., and Mostaghimi, A. (2018), “Cost of Routine Herpes Simplex Virus Infection Visits to U.S. Emergency Departments 2006-2013.” The western journal of emergency medicine, 19, 689–692. https://doi.org/10.5811/westjem.2018.3.37543.
Dommasch, E. D., Joyce, C. J., and Mostaghimi, A. (2017), “Trends in Nationwide Herpes Zoster Emergency Department Utilization From 2006 to 2013.” JAMA dermatology, 153, 874–881. https://doi.org/10.1001/jamadermatol.2017.1546.
Eguia, E., Bunn, C., Kulshrestha, S., Markossian, T., Durazo-Arvizu, R., Baker, M. S., Gonzalez, R., Behzadi, F., Churpek, M., Joyce, C., and Afshar, M. (2020), “Trends, Cost, and Mortality From Sepsis After Trauma in the United States: An Evaluation of the National Inpatient Sample of Hospitalizations, 2012-2016.” Critical care medicine, 48, 1296–1303. https://doi.org/10.1097/CCM.0000000000004451.
Elman, S. A., Joyce, C., Braudis, K., Chong, B. F., Fernandez, A. P., Furukawa, F., Hasegawa, M., Kim, H. J., Li, S. J., Lian, C. G., Szepietowski, J. C., Werth, V. P., and Merola, J. F. (2020), “Creation and Validation of Classification Criteria for Discoid Lupus Erythematosus.” JAMA dermatology, 156, 901–906. https://doi.org/10.1001/jamadermatol.2020.1698.
Elman, S. A., Joyce, C., Nyberg, F., Furukawa, F., Goodfield, M., Hasegawa, M., Marinovic, B., Szepietowski, J. C., Dutz, J., Werth, V. P., and Merola, J. F. (2017), “Development of classification criteria for discoid lupus erythematosus: Results of a Delphi exercise.” Journal of the American Academy of Dermatology, 77, 261–267. https://doi.org/10.1016/j.jaad.2017.02.030.
Hartman, R. I., Xue, Y., Karmouta, R., Tkachenko, E., Li, S. J., Li, D. G., Joyce, C., and Mostaghimi, A. (2022), “Development and Validation of a Simple Model to Predict the Risk of Nonmelanoma Skin Cancer on Screening Total Body Skin Examination.” Dermatology research and practice, 2022, 2313896. https://doi.org/10.1155/2022/2313896.
Hochstedler-Kramer, B., Joyce, C., Abdul-Rahim, O., Barnes, H. C., Mueller, E. R., Wolfe, A. J., Brubaker, L., and Burnett, L. A. (2022), “One Size Does Not Fit All: Variability in Urinary Symptoms and Microbial Communities,” Frontiers in Urology, 2, 890990. https://doi.org/10.3389/fruro.2022.890990.
Holt, E., Joyce, C., Dornelles, A., Morisky, D., Webber, L. S., Muntner, P., and Krousel-Wood, M. (2013), “Sex differences in barriers to antihypertensive medication adherence: Findings from the cohort study of medication adherence among older adults.” Journal of the American Geriatrics Society, 61, 558–564. https://doi.org/10.1111/jgs.12171.
Hussain, Z., Yu, M., Wozniak, A., Kim, D., Krepostman, N., Liebo, M., Raichlin, E., Heroux, A., Joyce, C., and Ilias-Basha, H. (2021), “Impact of donor smoking history on post heart transplant outcomes: A propensity-matched analysis of ISHLT registry.” Clinical transplantation, 35, e14127. https://doi.org/10.1111/ctr.14127.
Joyce, C., and Gomez, C. R. (2018), “Reimagining ARUBA: Theoretical Optimization of the Treatment of Unruptured Brain Arteriovenous Malformations.” Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 27, 3100–3107. https://doi.org/10.1016/j.jstrokecerebrovasdis.2018.07.007.
Joyce, C., Halverson, T., Gonzalez, C., Brubaker, L., and Wolfe, A. J. (2022a), “The Urobiomes of Adult Women With Various Lower Urinary Tract Symptoms Status Differ: A Re-Analysis.” Frontiers in cellular and infection microbiology, 12, 860408. https://doi.org/10.3389/fcimb.2022.860408.
Joyce, C., Markossian, T. W., Nikolaides, J., Ramsey, E., Thompson, H. M., Rojas, J. C., Sharma, B., Dligach, D., Oguss, M. K., Cooper, R. S., and Afshar, M. (2022b), “The Evaluation of a Clinical Decision Support Tool Using Natural Language Processing to Screen Hospitalized Adults for Unhealthy Substance Use: Protocol for a Quasi-Experimental Design.” JMIR research protocols, 11, e42971. https://doi.org/10.2196/42971.
Kinsinger, S. W., Joyce, C., Venu, M., and Palsson, O. S. (2022), “Pilot Study of a Self-Administered Hypnosis Intervention for Functional Dyspepsia.” Digestive diseases and sciences, 67, 3017–3025. https://doi.org/10.1007/s10620-021-07183-z.
Krousel-Wood, M., Joyce, C., Holt, E. W., Levitan, E. B., Dornelles, A., Webber, L. S., and Muntner, P. (2013), “Development and evaluation of a self-report tool to predict low pharmacy refill adherence in elderly patients with uncontrolled hypertension.” Pharmacotherapy, 33, 798–811. https://doi.org/10.1002/phar.1275.
Krousel-Wood, M., Peacock, E., Joyce, C., Li, S., Frohlich, E., Re, R., Mills, K., Chen, J., Stefanescu, A., Whelton, P., Tajeu, G., Kronish, I., and Muntner, P. (2019), “A hybrid 4-item Krousel-Wood Medication Adherence Scale predicts cardiovascular events in older hypertensive adults.” Journal of hypertension, 37, 851–859. https://doi.org/10.1097/HJH.0000000000001955.
Kulshrestha, S., Dligach, D., Joyce, C., Baker, M. S., Gonzalez, R., O’Rourke, A. P., Glazer, J. M., Stey, A., Kruser, J. M., Churpek, M. M., and Afshar, M. (2021a), “Prediction of severe chest injury using natural language processing from the electronic health record.” Injury, 52, 205–212. https://doi.org/10.1016/j.injury.2020.10.094.
Kulshrestha, S., Dligach, D., Joyce, C., Gonzalez, R., O’Rourke, A. P., Glazer, J. M., Stey, A., Kruser, J. M., Churpek, M. M., and Afshar, M. (2021b), “Comparison and interpretability of machine learning models to predict severity of chest injury.” JAMIA open, 4, ooab015. https://doi.org/10.1093/jamiaopen/ooab015.
Li, D. G., Dewan, A. K., Xia, F. D., Khosravi, H., Joyce, C., and Mostaghimi, A. (2018a), “The ALT-70 predictive model outperforms thermal imaging for the diagnosis of lower extremity cellulitis: A prospective evaluation.” Journal of the American Academy of Dermatology, 79, 1076–1080.e1. https://doi.org/10.1016/j.jaad.2018.06.062.
Li, D. G., Joyce, C., and Mostaghimi, A. (2018b), “Association Between Market Competition and Prices of Generic Topical Dermatology Drugs.” JAMA dermatology, 154, 1441–1446. https://doi.org/10.1001/jamadermatol.2018.3798.
Li, D. G., Joyce, C., and Mostaghimi, A. (2019), “Patient factors associated with nationwide emergency department utilization for cellulitis.” The American journal of emergency medicine, 37, 361–363. https://doi.org/10.1016/j.ajem.2018.06.037.
Li, D. G., Pournamdari, A. B., Liu, K. J., Laskowski, K., Joyce, C., and Mostaghimi, A. (2020), “Evaluation of Point-of-Care Decision Support for Adult Acne Treatment by Primary Care Clinicians.” JAMA dermatology, 156, 538–544. https://doi.org/10.1001/jamadermatol.2020.0135.
Li, N. Y., Bruce, W. J., Joyce, C., Decker, N. M., and Cappello, T. (2018c), “Obesity’s Influence on Operative Management of Pediatric Supracondylar Humerus Fractures.” Journal of pediatric orthopedics, 38, e118–e121. https://doi.org/10.1097/BPO.0000000000001126.
Liu, K. J., Hartman, R. I., Joyce, C., and Mostaghimi, A. (2016), “Modeling the Effect of Shared Care to Optimize Acne Referrals From Primary Care Clinicians to Dermatologists.” JAMA dermatology, 152, 655–660. https://doi.org/10.1001/jamadermatol.2016.0183.
Lowery, E. M., Walsh, M., Yong, M., Kovacs, E. J., Joyce, C., and Afshar, M. (2018), “Use of alcohol biomarkers to identify alcohol misuse in organ donors.” Alcohol (Fayetteville, N.Y.), 73, 67–72. https://doi.org/10.1016/j.alcohol.2018.03.010.
Loy, V. M., Joyce, C., Bello, S., VonRoenn, N., and Cotler, S. J. (2018), “Gender disparities in liver transplant candidates with nonalcoholic steatohepatitis.” Clinical transplantation, 32, e13297. https://doi.org/10.1111/ctr.13297.
Madsen, N., Joyce, C., Vlasses, F., and Burkhart, L. (2022), “Effectiveness of an interprofessional ambulatory care model on diabetes: evaluating clinical markers in a low-income patient population.” Journal of interprofessional care, 36, 500–508. https://doi.org/10.1080/13561820.2021.1941816.
Maureen Sheean, P., Robinson, P., Bartolotta, M. B., Joyce, C., Adams, W., and Penckofer, S. (2021), “Associations Between Cholecalciferol Supplementation and Self-Reported Symptoms Among Women With Metastatic Breast Cancer and Vitamin D Deficiency: A Pilot Study.” Oncology nursing forum, 48, 352–360. https://doi.org/10.1188/21.ONF.352-360.
Moll, J., Krieger, P., Heron, S. L., Joyce, C., and Moreno-Walton, L. (2019), “Attitudes, Behavior, and Comfort of Emergency Medicine Residents in Caring for LGBT Patients: What Do We Know?” AEM education and training, 3, 129–135. https://doi.org/10.1002/aet2.10318.
Raff, A. B., Weng, Q. Y., Cohen, J. M., Gunasekera, N., Okhovat, J.-P., Vedak, P., Joyce, C., Kroshinsky, D., and Mostaghimi, A. (2017), “A predictive model for diagnosis of lower extremity cellulitis: A cross- sectional study.” Journal of the American Academy of Dermatology, 76, 618–625.e2. https://doi.org/10.1016/j.jaad.2016.12.044.
Saban, K. L., Mathews, H. L., Bryant, F. B., Tell, D., Joyce, C., DeVon, H. A., and Witek Janusek, L. (2018), “Perceived discrimination is associated with the inflammatory response to acute laboratory stress in women at risk for cardiovascular disease.” Brain, behavior, and immunity, 73, 625–632. https://doi.org/10.1016/j.bbi.2018.07.010.
Sharma, B., Dligach, D., Swope, K., Salisbury-Afshar, E., Karnik, N. S., Joyce, C., and Afshar, M. (2020), “Publicly available machine learning models for identifying opioid misuse from the clinical notes of hospitalized patients.” BMC medical informatics and decision making, 20, 79. https://doi.org/10.1186/s12911-020-1099-y.
Singer, S., Li, D. G., Gunasekera, N., Okhovat, J.-P., Vedak, P., Weng, C., Cohen, J., Joyce, C., Raff, A., Kroshinsky, D., and Mostaghimi, A. (2019), “The ALT-70 cellulitis model maintains predictive value at 24 and 48 hours after presentation.” Journal of the American Academy of Dermatology, 81, 1252–1256. https://doi.org/10.1016/j.jaad.2019.03.050.
Southworth, E., Hochstedler, B., Price, T. K., Joyce, C., Wolfe, A. J., and Mueller, E. R. (2019), “A Cross-sectional Pilot Cohort Study Comparing Standard Urine Collection to the Peezy Midstream Device for Research Studies Involving Women.” Female pelvic medicine & reconstructive surgery, 25, e28–e33. https://doi.org/10.1097/SPV.0000000000000693.
Tan, S. Y., Feng, J. Y., Joyce, C., Fisher, J., and Mostaghimi, A. (2020), “Association of Hospital Discharge Against Medical Advice With Readmission and In-Hospital Mortality.” JAMA network open, 3, e206009. https://doi.org/10.1001/jamanetworkopen.2020.6009.
Tenfelde, S., Joyce, C., Tell, D., Masinter, L., Wallander-Gemkow, J., and Garfield, L. (2022), “Reducing Disparities in Postpartum Care Utilization: Development of a Clinical Risk Assessment Tool.” Journal of midwifery & women’s health. https://doi.org/10.1111/jmwh.13461.
Thomas-White, K., Taege, S., Limeira, R., Brincat, C., Joyce, C., Hilt, E. E., Mac-Daniel, L., Radek, K. A., Brubaker, L., Mueller, E. R., and Wolfe, A. J. (2020), “Vaginal estrogen therapy is associated with increased Lactobacillus in the urine of postmenopausal women with overactive bladder symptoms.” American journal of obstetrics and gynecology, 223, 727.e1–727.e11. https://doi.org/10.1016/j.ajog.2020.08.006.
To, D., Sharma, B., Karnik, N., Joyce, C., Dligach, D., and Afshar, M. (2020), “Validation of an alcohol misuse classifier in hospitalized patients.” Alcohol (Fayetteville, N.Y.), 84, 49–55. https://doi.org/10.1016/j.alcohol.2019.09.008.
Williams, L. G., Peacock, E., Joyce, C., Bazzano, L. A., Sarpong, D., Whelton, P. K., Holt, E. W., Re, R., Frohlich, E., He, J., Muntner, P., and Krousel-Wood, M. (2018), “Risk Factors for Low Pharmacy Refill Adherence Among Older Hypertensive Men and Women by Race.” The American journal of the medical sciences, 356, 464–475. https://doi.org/10.1016/j.amjms.2018.07.007.
Wolff, B. J., Price, T. K., Joyce, C. J., Wolfe, A. J., and Mueller, E. R. (2019), “Oral probiotics and the female urinary microbiome: A double-blinded randomized placebo-controlled trial.” International urology and nephrology, 51, 2149–2159. https://doi.org/10.1007/s11255-019-02282-3.
Xia, F. D., Joyce, C., and Mostaghimi, A. (2017), “Estimated Cost of Emergency Sunburn Visits-Validation of ICD-9-CM Search Criteria.” JAMA dermatology, 153, 612–613. https://doi.org/10.1001/jamadermatol.2017.0252.
Zhu, J., Hazen, R. J., Joyce, C., Delpino, A., Kirkham, H. S., Strickland, C. D., Markes-Wilson, S., Kim, T., Kang, M., Rubin, R. A., and Stein, L. L. (2018), “Local specialty pharmacy and specialty clinic collaboration assists access to hepatitis C direct-acting antivirals.” Journal of the American Pharmacists Association : JAPhA, 58, 89–93.e2. https://doi.org/10.1016/j.japh.2017.10.011.
Zilliox, M. J., Gange, W. S., Kuffel, G., Mores, C. R., Joyce, C., Bustros, P. de, and Bouchard, C. S. (2020), “Assessing the ocular surface microbiome in severe ocular surface diseases.” The ocular surface, 18, 706–712. https://doi.org/10.1016/j.jtos.2020.07.007.